17.00 Uhr im Seminarraum 1.27 Von-Danckelmann-Platz 4, 06120 Halle
TIFR Center for Interdisciplinary Sciences, 21 Brundavan Colony, Narsinghi, Hyderabad 500075, India
“Understanding amyloid-β aggregation and toxicity by NMR spectroscopy”
Abstract:
The aggregation and membrane association of amyloid- peptides is correlated with their toxicity to living cells. This is believed to be directly responsible for the progression of neurodegenerative diseases such as the Alzheimer’s disease. However, the presence of a number of intermediate species along the aggregation pathway makes it difficult correlate the toxicity to a specific structure….