17.15 Uhr im Seminarraum 1.27 Von-Danckelmann-Platz 4, 06120 Halle
University of Groningen, Netherlands
“Quantification and consequences of macromolecular crowding”
Abstract:
Cells are highly crowded with proteins and polynucleotides, with concentrations ranging from 80 to 400 mg/mL. Knowledge of crowding is critical to understand cell physiology and to assess its relevance for medical science and biotechnology: Any reaction that depends on the available volume can be affected by crowding, which includes diffusion, conformation, association, folding, phase separation, and aggregation of the biopolymers….
